Figure 1.
Effects of ethanol upon neural crest development. Although chick embryos are depicted, these changes have been documented in diverse vertebrate species including mouse, zebrafish, and Xenopus. The left-half of each embryo depicts normal development, and each right-half contrasts the consequences of ethanol exposure. Details of these changes are presented in the text. Purple, shh; teal, neural crest; blue, chondrogenesis; red dots, apoptosis; pink stars, ROS; teal squiggles, migrating neural crest. Cont, control; EtOH, ethanol; NC, neural crest; PCM, prechordal plate; ROS, reactive oxygen species.