Table 2.
Univariate and multivariable Cox regression analyses containing main and interaction effects of potential covariates on time until opioid relapse.
| COVARIATES | UNIVARIATE ANALYSES | MULTIVARIABLE ANALYSES* | ||
|---|---|---|---|---|
| HAZARD RATIO (95% CI) | P-VALUE | HAZARD RATIO (95% CI) | P-VALUE | |
| Current age (years) | 1.00 (0.98, 1.02) | 0.982 | 0.93 (0.89, 0.97) | 0.003 |
| Days of illicit benzodiazepine use (days) | 1.06 (1.01, 1.10) | 0.009 | 1.07 (1.03, 1.12) | 0.002 |
| Age of onset of opioid abuse (years) | 1.02 (1.00, 1.04) | 0.115 | 1.10 (1.04, 1.15) | <0.0001 |
| Injecting drug use behavior | 2.25 (1.12, 4.47) | 0.022 | 2.26 (1.03, 4.97) | 0.042 |
| Age *Methadone dose (mg/day) | – | – | 0.99 (0.98, 1.00) | 0.063 |
| Age *Hepatitis C | – | – | 1.01 (1.00, 1.03) | 0.020 |