Table 3. Quantification of the Lumen and Intimal Thickness of the Carotid In Normal, Untreated and PPS Treated MPS I Dogs.

	Left	Carotid	Right	Carotid
	Lumen (μm)	Thickness (μm)	Lumen (μm)	Thickness (μm)
Normal	72.5 (69.9–75.9)	73.1 (70.2–77.3)	91.9 (84.2–94.6)	79.9 (77.5–87.1)
Untreated	33.3 (29.9–37.7)	146.7 (108.8–192.7)	61.8 (54.3–64.1)	110.0 (101.5–137.9)
Oral PPS	75.1*(70.1–78.1)	91.8* (86.7–95.9)	85.3* (79.7–89.1)	91.1* (89.1–93.2)
SQ PPS	80.3*# (74.6–80.1)	79.0*#(73.7–92.4)	90.1*# (87.4–93.9)	83.8*# (79.9–89.9)

*P<0.01 when comparing untreated to PPS treated animals. There is also a significant effect when comparing oral to SQ treatment

^#P<0.01. Ranges shown in ().