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. 2016 Apr 11;12(4):e1005537. doi: 10.1371/journal.ppat.1005537

Fig 14. Neutralization epitopes of SIV Env modeled onto the 3D structure of HIV-1 BG505 SOSIP.664 trimer.

Fig 14

Pre-fusion HIV-1 BG505 trimer structure (PDB ID: 4TVP) is displayed in ribbon representation with red for CD4-binding-site-directed antibody specificities (VRC01-, b12-, CD4-, and HJ16-like), purple for 8ANC195-like, green for V1V2-directed (PG9-like), blue for glycan-V3 specificities (PGT128- and 2G12-like), orange for 35O22-like specificities, and green-yellow for PGT151-like specificities. Epitope targets of SIV Env neutralizing mAbs are shown as spheres with red for CD4-binding-site-, green for V1V2-, and blue for V3-directed specificities. Top (left) and side (right) views are shown.