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. Author manuscript; available in PMC: 2016 Apr 11.
Published in final edited form as: J Mol Cell Cardiol. 2015 Jan 7;80:114–125. doi: 10.1016/j.yjmcc.2014.12.021

Figure 8. Effect of PI3K-IA inhibition by PI-103 on ouabain-induced PKCε activation.

Figure 8

Hearts were perfused for 4 min with or without ouabain and/or PI-103 according to Protocol A (Figure 1). Cytosolic (C) and particulate (P) fractions were prepared from heart lysates as described in Methods and P/C ratios of PKCε contents were compared. Upper panel: representative western blot. Lower panel: means ± SEM of 3-5 separate experiments. *** P< 0.001 vs. C, ## P < 0.01 vs. PI-103.