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. 2016 Apr 7;9:2081–2088. doi: 10.2147/OTT.S95414

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© 2016 Ye et al. This work is published and licensed by Dove Medical Press Limited

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Effects of HOTTIP on the biological behaviors of SGC-7901 and MKN-28 cells.

Notes: (A) Expression of HOTTIP was significantly downregulated after si-HOTTIP transfection. *P<0.05. (B) Cell proliferation was measured by MTT assays in SGC-7901 and MKN-28 cells transfected with si-HOTTIP or si-NC. **P<0.01. (C) Flow cytometric analysis showed induced cell apoptosis after si-HOTTIP transfection. (D, E) The transwell invasion and migration assays showed that the number of invaded or migrated cells was significantly lower in the si-HOTTIP-transfected group than in the si-NC-transfected group. *P<0.05.

Abbreviations: HOTTIP, HOXA transcript at the distal tip; h, hour; si-HOTTIP, HOTTIP small interfering RNA; si-NC, nontargeting small interfering RNA; OD, optical density.

Effects of HOTTIP on the biological behaviors of SGC-7901 and MKN-28 cells.

Notes: (A) Expression of HOTTIP was significantly downregulated after si-HOTTIP transfection. *P<0.05. (B) Cell proliferation was measured by MTT assays in SGC-7901 and MKN-28 cells transfected with si-HOTTIP or si-NC. **P<0.01. (C) Flow cytometric analysis showed induced cell apoptosis after si-HOTTIP transfection. (D, E) The transwell invasion and migration assays showed that the number of invaded or migrated cells was significantly lower in the si-HOTTIP-transfected group than in the si-NC-transfected group. *P<0.05.

Abbreviations: HOTTIP, HOXA transcript at the distal tip; h, hour; si-HOTTIP, HOTTIP small interfering RNA; si-NC, nontargeting small interfering RNA; OD, optical density.