Table 1.
Correlation between HOTTIP expression and different clinicopathological features in patients with gastric cancer
| Characteristics | High HOTTIP expression (%) | Low HOTTIP expression (%) | P-value |
|---|---|---|---|
| Age (years) | |||
| ≥60 | 34 (47.9) | 37 (52.1) | 0.652 |
| <60 | 15 (55.6) | 12 (44.4) | |
| Sex | |||
| Male | 26 (46.4) | 30 (53.6) | 0.541 |
| Female | 23 (54.8) | 19 (45.2) | |
| Differentiation | |||
| Well-moderate | 12 (40.0) | 18 (60.0) | 0.273 |
| Poor | 37 (54.4) | 31 (45.6) | |
| Lauren type | |||
| Intestinal | 27 (43.5) | 35 (56.5) | 0.142 |
| Diffuse and mixed | 22 (61.1) | 14 (38.9) | |
| Tumor size | |||
| ≥5 cm | 36 (61.0) | 23 (39.0) | 0.006 |
| <5 cm | 13 (33.3) | 26 (66.7) | |
| Invasion depth | |||
| T1, T2 | 14 (36.8) | 24 (63.2) | 0.031 |
| T3, T4 | 35 (58.3) | 25 (41.7) | |
| TNM stage | |||
| I/II | 11 (33.3) | 22 (66.7) | 0.013 |
| III | 38 (58.5) | 27 (41.5) | |
| Lymphatic metastasis | |||
| Negative | 10 (33.3) | 20 (66.7) | 0.028 |
| Positive | 39 (57.4) | 29 (42.6) |
Abbreviation: HOTTIP, HOXA transcript at the distal tip.