Table 3.
Plasma vitamin D level according to GC variants and genotypes
| Variables | Participants (N) | Vitamin D level, ng/mL* | Vitamin D deficiency# |
|---|---|---|---|
| Variant | |||
| GC1F | 120 | 18.3±9.6 | 79 (65.8) |
| Non-GC1F | 55 | 15.7±9.0 | 43 (78.2) |
| P-value | 0.094 | 0.099 | |
| GC1S | 75 | 18.3±10.7 | 52 (69.3) |
| Non-GC1S | 100 | 16.9±8.5 | 70 (70.0) |
| P-value | 0.328 | 0.924 | |
| GC2 | 95 | 15.5±8.8 | 75 (78.9) |
| Non-GC2 | 80 | 19.9±9.7 | 47 (58.8) |
| P-value | 0.002 | 0.004 | |
| Genotype | |||
| 1F-1F | 35 | 18.5±7.0 | 20 (57.1) |
| Non-1F-1F | 140 | 17.3±10.0 | 102 (72.9) |
| P-value | 0.500 | 0.070 | |
| 1F-1S | 37 | 20.7±11.4 | 23 (62.2) |
| Non-1F-1S | 138 | 16.7±8.8 | 99 (71.7) |
| P-value | 0.021 | 0.260 | |
| 1F-2 | 48 | 16.4±9.5 | 36 (75.0) |
| Non-1F-2 | 127 | 17.9±9.5 | 86 (67.7) |
| P-value | 0.336 | 0.350 | |
| 1S-1S | 8 | 22.2 (11.7–33.6) | 4 (50.0) |
| Non-1S-1S | 167 | 15.5 (10.9–22.0) | 118 (70.7) |
| P-value | 0.189 | 0.246 | |
| 1S-2 | 30 | 14.2±8.1 | 25 (83.3) |
| Non-1S-2 | 145 | 18.2±9.6 | 97 (66.9) |
| P-value | 0.034 | 0.075 | |
| 2-2 | 17 | 15.0 (8.1–19.9) | 14 (82.4) |
| Non-2-2 | 158 | 15.8 (11.3–22.8) | 108 (68.4) |
| P-value | 0.164 | 0.233 |
Notes:
*
Data are presented as mean ± standard deviation, median (interquartile range) or P-value.
#
Data are presented as the number of patients (percentage) or P-value. Vitamin D deficiency was defined as plasma level of 25-hydroxyvitamin D3 lower than 20 ng/mL.