Table 1.
Composition of the probiotics-loaded ECPs-T formulation
| Excipients | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 |
|---|---|---|---|---|---|---|---|---|---|
| ECPs | 335 | 335 | 335 | 335 | 335 | 335 | 335 | 335 | 335 |
| L-HPC 11 | 22.5 | 22.5 | 22.5 | 22.5 | 22.5 | 22.5 | 22.5 | 22.5 | 22.5 |
| Crospovidone | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 |
| HPC-EXF | 20 | 20 | 20 | 20 | 20 | 20 | 20 | 20 | 20 |
| Avicel PH102 | 37.5 | – | – | – | – | – | 37.5 | 37.5 | 37.5 |
| Lactose monohydrate | – | 37.5 | – | – | – | – | – | – | – |
| Corn starch | – | – | 37.5 | – | – | – | – | – | – |
| Avicel PH105 | – | – | – | 37.5 | – | – | – | – | – |
| Avicel PH101 | – | – | – | – | 37.5 | – | – | – | – |
| Avicel PH200 | – | – | – | – | – | 37.5 | – | – | – |
| Calcium silicate | – | – | – | – | – | – | 15 | 25 | 35 |
| Magnesium stearate | 15 | 15 | 15 | 15 | 15 | 15 | 15 | 15 | 15 |
Note: Unit of measurement is mg; “–” indicates not added or not included in the formula.
Abbreviations: ECPs-T, enteric-coated pellets embedded tablet; ECPs, enteric-coated pellets; F, formulation; HPC, hydroxypropylcellulose; L-HPC, low-substituted hydroxypropyl cellulose.