Skip to main content
. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: J Thromb Haemost. 2016 Mar 16;14(4):815–827. doi: 10.1111/jth.13270

Figure 5. Adult and neonatal platelet adhesion and aggregation under fluid shear conditions.

Figure 5

(A) Representative differential interference contrast images and corresponding fluorescent CD41a-PE and CD62P-FITC images of adult and neonatal platelet aggregates formed in a small-volume flow chamber coated with 100 μg/mL von Willebrand factor (VWF) or 100 μg/mL fibrillar collagen at 200 or 1500 s−1 shear rate for 30 s. The black arrow denotes direction of blood flow. Mean percent surface area coverage of a 140 × 105 μm field of view of adult and neonatal platelet aggregates positive for CD41a-PE formed in flow chambers coated with VWF (B) or collagen (C). Data are represented as mean ± SEM; Nadult = 3 and Nneonate = 3; *P < 0.05 with respect to 200 s−1 shear rate.