Fig. 5.

GC formation is severely abrogated in CXCL13^−/− mice. GC formation in the CLN of WT and CXCL13^−/− mice at day 21 p.i. analyzed using DAPI (blue), anti-GL7 (green) and anti-B220 (red) Ab. GL7⁺ B cells are absent or sparse in naïve WT and CXCL13^−/− mice respectively. Merged images are shown. Photomicrographs are presented at a magnification of 40×. Scale bar is 50 μm. White-boxed area shown in bottom row photomicrographs. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)