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. Author manuscript; available in PMC: 2016 Dec 15.
Published in final edited form as: Bioorg Med Chem. 2015 Dec 15;23(24):7497–7520. doi: 10.1016/j.bmc.2015.10.012

Figure 1.

Figure 1

Representative small-molecule inhibitors of tubulin polymerization: colchicine, combretastatins (CA4, CA1),2021 dihydronaphthalene analogue (OXi6196),3032 benzosuberene analogues (KGP18 and KGP156),30,33,34 indole analogue (OXi8006)35 and benzo[b]furan analogue (BNC105).36