| ULK1 |
T180 |
ULK1 autophosphorylation |
Activation loop in catalytic domain |
Stimulates ULK1 kinase activity |
40 |
|
S317 |
AMPK |
IDR |
Stimulates ULK1 kinase activity |
22 |
| S467 |
AMPK |
IDR |
Required for mitochondrial homeostasis during
starvation |
25 |
| S555 |
AMPK |
IDR |
Required for mitochondrial homeostasis during
starvation, regulates Atg9 localization |
25,
26, 27
|
| T574 |
AMPK |
IDR |
Required for mitochondrial homeostasis during
starvation |
25 |
| S637 |
mTORC1 |
IDR |
Promotes ULK1-AMPK interaction |
26 |
| AMPK |
Required for mitochondrial homeostasis during
starvation, regulates Atg9 localization |
25,27
|
| S659 |
AMPK |
IDR |
Regulates Atg9 localization |
27 |
| S757 |
mTORC1 |
IDR |
Inhibits ULK1 kinase activity |
22,
25, 26
|
| S777 |
AMPK |
IDR near N-terminus of EAT domain |
Stimulates ULK1 kinase activity |
22,
25
|
| ATG13 |
S224 |
AMPK |
IDR |
Inhibits ULK1 kinase activity |
23 |
| S258 |
mTORC1 |
IDR |
Inhibits ULK1 kinase activity |
23 |
| S389 |
ULK1 |
IDR |
Unknown |
37 |
| ATG101 |
S11 |
ULK1 |
HORMA |
Unknown |
37 |
| S203 |
ULK1 |
Flexible region just past C-terminus of
HORMA |
Unknown |
37 |
| FIP200 |
S943 |
ULK1 |
Coiled coil |
Unknown |
37 |
| S989 |
ULK1 |
Coiled coil |
Unknown |
37 |
| S1323 |
ULK1 |
Coiled coil |
Unknown |
37 |