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Neonatal anticonvulsant exposure results in decreased center exploration, without altering total activity, in the open field task.
(A) Distance traveled in the open field as a function of time. Error bars = +/− SEM (B) Time spent in the center of the open field as a function of treatment. Bars show mean + SEM. * indicates significantly different than control (P<0.05). Decreased time in the center of the open field is consistent with increased anxiety-like behavior.
