Table 1.
Colonization of CA in kidneys of immunized mice.
| Treatment groupa | CFU in Kidney (log10/g of kidney)b | pc |
|---|---|---|
| rSap2 | 2.34±0.04 | <0.05 |
| EPSP nanofibers | 2.71±0.09 | <0.05 |
| WTP nanofibers | 3.29±0.04 | NS (not significant) |
| PBS | 3.37±0.02 |
a
One week after the third time immunization with rSap2, EPSP, WTP or PBS, mice were inoculated with 2×106 CA cells.
b
Kidneys of mice were collected, weighed and homogenized with a glass grinder in sterile physiological saline. Then CFU of CA in kidneys was counted.
c
Statistic analysis with student’s t-test showed that immunization with EPSP (p<0.05) or rSap2 (p<0.05) significantly decreased the CFU in kidneys of mice against candidiasis compared with PBS group and WTP group.