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. Author manuscript; available in PMC: 2017 Apr 6.
Published in final edited form as: Adv Healthc Mater. 2016 Feb 18;5(7):786–794. doi: 10.1002/adhm.201500930

Table 2.

CFU in kidneys of mice treated with antibody

Treatment groupsa CFUs in Kidneyb (log10/g of kidney) pc
rSap2 1.30±0.46 <0.01
EPSP nanofibers 1.34±0.54 <0.05
WTP nanofibers 2.47±0.55 NS (not significant)
PBS 2.45±0.46
a

Mice were inoculated with 100 µL PBS containing 2×107 CA cells via an intravenous injection. Four hours later, 6 mice each group were chosen randomly for treatment with the reagents below: (1) 100 µl of purified antibody against rpSap2 at a dose of 5.0 mg/kg mice weight; (2) 100 µl of purified antibody against EPSP at a dose of 5.0 mg/kg mice weight; (3) 100 µl of purified antibody against WTP at a dose of 5.0 mg/kg mice weight; (4) 100 µl PBS at a dose of 5.0 mg/kg mice weight.

b

Two days after injection of antibodies, kidneys of mice were collected, weighed and homogenized with a glass grinder in sterile physiological saline. CFUs were counted and recorded.

c

Difference analysis with student’s t-test showed that the EPSP antibody (p<0.05) and rSap2 (p<0.01) antibody greatly decreased the CFU in kidneys of mice against candidiasis compared with the control (PBS) group.