Table 3.

Univariate analysis of predictors for non-referral for transplant evaluation

Predictors	OR (95% CI)	P Value
Age (per 5 year increase)	1.11 (1.04, 1.18)	0.001
Male gender	1.33 (1.05, 1.69)	0.020
Acute exacerbations per year	0.90 (0.85, 0.95)	<0.001
Positive sputum culture:
Burkholderia cepacia complex	1.89 (1.24, 2.88)	0.003
Supplemental oxygen	0.60 (0.47, 0.76)	<0.001
<4 outpatient visits per year	1.96 (1.49, 2.57)	<0.001
Not a high school graduate	2.21 (1.47, 3.33)	<0.001
Insurance status – Medicaid vs. no Medicaid	1.46 (1.15, 1.85)	0.002
Median income relative to FPL
>300% FPL	REF
250–300% FPL	1.11 (0.77, 1.59)	0.590
200–250% FPL	1.17 (0.84, 1.64)	0.346
<200% FPL	1.57 (1.13, 2.18)	0.008
Driving time to lung transplant center
<30 min (1st quartile)	REF
30–75 min (2nd quartile)	1.07 (0.75, 1.51)	0.718
75–150 min (3rd quartile)	1.10 (0.78, 1.55)	0.577
>150 min (4th quartile)	1.44 (1.03, 2.02)	0.033

OR = odds ratio; CI = confidence interval; FPL = federal poverty level; min = minutes

The following covariates had non-significant associations with referral status: Race (OR 1.00, p=0.994), FEV1 (OR 1.01, p=0.515), BMI (OR 0.98, p=0.389), CF-related diabetes on insulin (OR 0.87, p=0.299), NTM culture positive (OR 0.40, p=0.102), CF-related liver cirrhosis (OR 0.85, p=0.603), Renal failure requiring dialysis (OR 0.21, p=0.136), Osteoporosis (OR = 0.68, p=0.054), Cancer, tissue proven (OR 0.47, p=0.498), Depression (OR 1.23, p=0.127), No marital partner (OR 1.15, p=0.272), pre-LAS (OR 0.85, p=0.166)