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. Author manuscript; available in PMC: 2016 Apr 12.
Published in final edited form as: Biochem J. 2015 Apr 27;469(1):71–82. doi: 10.1042/BJ20141455

Figure 3. Bioinformatic analysis of pathways altered by adiponectin or not.

Figure 3

HFD compared with chow enriched pathway network highlighting pathways rescued (A) and not rescued (B) by adiponectin. Enriched pathways in HFD compared with chow are annotated with node labels and colours indicating the direction of metabolite expression, where red is up-regulated, blue is down-regulated and white indicates there was no change. The transparency of the nodes was increased in (A) if it was a pathway not seen in the HFD + adiponectin compared with HFD enriched pathway set to highlight pathways (common to both HFD compared with chow and HFD±adiponectin compared with HFD) that were rescued by adiponectin. The transparency of the nodes was increased in (B) if it was a pathway found in HFD + adiponectin compared with HFD enriched pathway set to highlight pathways unique to HFD compared with chow and not rescued by adiponectin.