Table 5. Features of the twopatients with Hashimoto's thyroiditis who showed improved urticaria after treatment with levothyroxine.
| Patient no. | Sex/age (yr) | Dose of LT4 (mg/day) | Time to remission (wk) | Before/after | Medication requirements before LT4 therapy | Outcome | |||
|---|---|---|---|---|---|---|---|---|---|
| TSH* | FT4* | Anti-TPO Ab* | Anti-TG Ab* | ||||||
| 1 | 1 Female/51 | 0.05~0.1 | 6 | 6.45/3.43 | 0.85/1.52 | 138.3/109.4 | 528.4/485.4 | Azelastine, levocetirizine, olopatadine | No hives for 6 mo; LT4 |
| 2 | Female/31 | 0.05~0.1 | 8 | 7.00/2.96 | 0.74/1.11 | >600/ND | 305.5/ND | Prednisolone, fexofenadine, levocetirizine, ebastine, pemirolast | Rare hives for >1 yr; LT4, Ebastine (prn only) |
LT4: levothyroxine, TSH: thyroid-stimulating hormone, FT4: free T4, TPO: thyroperoxidase, Ab: antibodies, TG: thyroglobulin, ND: test not done, prn: as needed. *Normal values: TSH, 0.27~4.20 µU/ml; FT4, 0.93~1.70 ng/dl; anti-TPO Ab, 0~34.00 IU/dl; anti-TG Ab, 0~115.00 IU/dl.