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. 2016 Mar 31;28(2):199–204. doi: 10.5021/ad.2016.28.2.199

Table 5. Features of the twopatients with Hashimoto's thyroiditis who showed improved urticaria after treatment with levothyroxine.

Patient no. Sex/age (yr) Dose of LT4 (mg/day) Time to remission (wk) Before/after Medication requirements before LT4 therapy Outcome
TSH* FT4* Anti-TPO Ab* Anti-TG Ab*
1 1 Female/51 0.05~0.1 6 6.45/3.43 0.85/1.52 138.3/109.4 528.4/485.4 Azelastine, levocetirizine, olopatadine No hives for 6 mo; LT4
2 Female/31 0.05~0.1 8 7.00/2.96 0.74/1.11 >600/ND 305.5/ND Prednisolone, fexofenadine, levocetirizine, ebastine, pemirolast Rare hives for >1 yr; LT4, Ebastine (prn only)

LT4: levothyroxine, TSH: thyroid-stimulating hormone, FT4: free T4, TPO: thyroperoxidase, Ab: antibodies, TG: thyroglobulin, ND: test not done, prn: as needed. *Normal values: TSH, 0.27~4.20 µU/ml; FT4, 0.93~1.70 ng/dl; anti-TPO Ab, 0~34.00 IU/dl; anti-TG Ab, 0~115.00 IU/dl.