Table 3.
Brain areas showing significant interactions for resting-state functional connectivity using a 2 (between-subject factor: training and control groups) × 2 (within-subject factor: baseline and 1-year after training ended) repeated ANOVA.
| Seed | Brain region | BA | MNI coordinate |
F-score | Cluster size (mm3) | ||
|---|---|---|---|---|---|---|---|
| X | Y | Z | |||||
| PCC | Left dorsolateral prefrontal lobe | 20 | -33 | 15 | 24 | 18.64 | 2187 |
| Left cerebellar lobule IX | -6 | -51 | -54 | 16.2 | 2241 | ||
| Right putamen | 9 | 18 | 15 | -9 | 13.17 | 1377 | |
| Right dorsolateral prefrontal lobe | 51 | 0 | 30 | 12.86 | 1782 | ||
| Left superior frontal gyrus | 20 | -24 | 36 | 39 | 11.66 | 1323 | |
| Right AI | Right insula | 45 | 30 | -9 | -18 | 15.82 | 4644 |
| Left frontoinsula | 45 | -51 | 33 | -12 | 11.67 | 2538 | |
| Right DLPFC | Right superior frontal cortex | 11 | 15 | 27 | 54 | 13.30 | 3186 |
| Left dorsolateral prefrontal cortex | 9 | -39 | 30 | 42 | 12.78 | 1647 | |
| Left inferior parietal lobe | -30 | -63 | 30 | 13 | 1431 | ||
| Right superior frontal gyrus | 42 | 27 | 42 | 12.12 | 2970 | ||
BA, Broadmann area; CEN, central executive network; DMN, default mode network; SN, salience network; DLPFC, dorsolateral prefrontal cortex; AI, anterior insula; PCC, posterior cingulate cortex.