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. 2016 Apr 12;7:84. doi: 10.3389/fphar.2016.00084

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Copyright © 2016 Lu, Huang, Mo and Zhao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Modeling cancer with cellular reprogramming technology. (A) Premature termination of reprogramming leads to tumor development. (B) Re-differentiation of cancer cell-derived iPSC can recapitulate the progression of human cancer development.