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. 2016 Apr 12;7:84. doi: 10.3389/fphar.2016.00084

Table 1.

List of NPs targeting CSC through specific markers or signaling pathways.

Type of nanoparticle Target Anticancer agent Type of cancer Reference
Liposomes Nucleolin, CD44 F3 peptide, γ-secretase inhibitors (GSIs), Tamoxifen, Paclitaxel Triple negative breast cancer (TNBC) Parvani et al., 2015
Micelles ALDH1A1, CD44 Paclitaxel (PTX), anti-CD44 antibodies, Cetuximab (anti-EGFR), phenformin, gemcitabine, thioridazine (THZ), Twist1 siRNA Breast cancer, lung cancer Gener et al., 2015; Krishnamurthy et al., 2015b
Polymeric nanoparticles ALDH, CD133 Hedgehog pathway inhibitor (HPI) Brain tumor Lim et al., 2011; Chenna et al., 2012
Gold nanoparticles TGF-β, acid-labile hydrazone bond Doxorubicin Breast cancer Sun et al., 2014