Table 2.

Results from univariable Cox regressions for mortality risk prediction, within 1 year of follow-up in older cancer patients

Variable	Category	HR (95 % CI)	p value
Age	Cont. Var.	1.076 (1.039–1.114)	<0.001
Sex	Male versus female	2.084 (1.422–3.056)	<0.001
BMI	Cont. Var.	0.870 (0.824–0.918)	<0.001
ADL	Cont. Var.	0.667 (0.582–0.764)	<0.001
IADL	Cont. Var.	0.765 (0.709–0.825)	<0.001
The presence of comorbidity	Yes versus no	1.420 (0.941–2.145)	0.095
Comorbidity Index CIRS	Cont. Var.	1.011 (0.873–1.173)	0.880
No of total comorbidites CIRS	Cont. Var.	1.036 (0.921–1.164)	0.557
No of severe comorbidites CIRS	Cont. Var.	1.288 (0.985–1.685)	0.065
MMSE	<24 versus ≥24	1.913 (1.253–2.922)	0.003
Psychiatric diseases	Yes versus no	0.809 (0.376–1.742)	0.589
Cancer stage	IV versus I	17.089 (8.189–35.659)	<0.001
	III versus I	4.555 (1.966–10.555)	<0.001
	II versus I	3.614 (1.546–8.443)	0.003
Cancer treatment	Yes versus no	0.726 (0.478–1.105)	0.135
No of drugs	Cont. Var.	1.036 (0.960–1.117)	0.363
Performance status (continuous)	Cont. Var.	2.133 (1.766–2.576)	<0.001
ECOG performance status (categorical)	≥3 versus 0	6.184 (2.163–17.679)	<0.001
	2 versus 0	7.418 (4.223–13.031)	<0.001
	1 versus 0	4.232 (2.658–6.738)	<0.001
Caregiver	Yes versus no	1.603 (1.002–2.565)	0.049
15-item Geriatric Depression Scale	>5 versus ≤5	1.402 (0.926–2.125)	0.111
Syndromes	Yes versus no	1.329 (0.693–2.550)	0.392
Tumor site	Breast versus other	0.078 (0.038–0.157)	<0.001
	Colorectal versus other	0.401 (0.234–0.685)	<0.001
	Lung versus other	1.429 (0.815–2.506)	0.213
	Prostate versus other	0.335 (0.131–0.856)	0.022
	Other genitourinary versus other	1.372 (0.747–2.520)	0.308

BMI body mass index, ADL activities of daily living, IADL instrumental activities of daily living, CIRS Cumulative Illness Rating Scale, MMSE mini-mental state examination, ECOG Eastern Cooperative Oncology Group, Cont. Var. continuous variable