Table 4.

Results from multivariable Cox regressions for mortality risk prediction, within 1 year of follow-up in older cancer patients

Variable	Category	HR (95 % CI)	p value
Age	Cont. Var.	1.040 (0.996–1.086)	0.075
Sex	Male versus female	1.018 (0.647–1.600)	0.939
BMI	Cont. Var.	0.912 (0.859–0.968)	0.002
ADL	Cont. Var.	0.920 (0.751–1.128)	0.423
IADL	Cont. Var.	1.008 (0.870–1.167)	0.92
Comorbidity index CIRS	Cont. Var.	0.914 (0.749–1.114)	0.372
MMSE	<24 versus ≥24	0.971 (0.595–1.584)	0.906
Psychiatric diseases	Yes versus no	0.498 (0.198–1.251)	0.138
Cancer stage	IV versus I	6.689 (2.950–15.166)	<0.001
	III versus I	2.129 (0.854–5.306)	0.105
	II versus I	3.335 (1.389–8.009)	0.007
Cancer treatment	Yes versus no	0.984 (0.618–1.567)	0.945
No of drugs	Cont. Var.	1.023 (0.923–1.133)	0.668
ECOG performance status	≥3 versus 0	7.747 (1.744–34.411)	0.007
	2 versus 0	3.827 (1.777–8.244)	<0.001
	1 versus 0	3.122 (1.877–5.191)	<0.001
Caregiver	Yes versus no	1.193 (0.708–2.010)	0.508
15-item Geriatric Depression Scale	>5 versus ≤5	0.947 (0.574–1.564)	0.833
Syndromes	Yes versus no	1.050 (0.494–2.234)	0.898
Tumor site	Breast versus other	0.164 (0.068–0.396)	<0.001
	Colorectal versus other	0.379 (0.214–0.671)	<0.001
	Lung versus other	1.407 (0.767–2.579)	0.270
	Prostate versus other	0.209 (0.073–0.599)	0.004
	Other genitourinary versus other	1.260 (0.652–2.433)	0.492

BMI body mass index, ADL activities of daily living, IADL instrumental activities of daily living, CIRS Cumulative Illness Rating Scale, MMSE mini-mental state examination, ECOG Eastern Cooperative Oncology Group, Cont. Var. continuous variable