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Promoter methylation frequency of RGC32 gene in breast cancerous and breast normal tissues.
|
RGC32
methylation status |
Normal tissues | Breast tumors | OR (95% CI) | P value |
|---|---|---|---|---|
| UU (%) | 55 (87.3) | 49 (77.8) | Ref. | — |
| UM (%) | 8 (12.7) | 11 (17.5) | 1.54 (0.58–4.15) | 0.390 |
| MM (%) | 0 (0) | 3 (4.8) | (0.001) | 0.999 |
| Methylation | ||||
| Absent | 118 (93.6) | 109 (86.5) | Ref. | — |
| Present | 8 (6.4) | 17 (13.5) | 2.30 (0.95–5.54) | 0.090 |
UU: fully unmethylated promoter; UM: semimethylated promoter; MM: fully methylated promoter.
