Table 2.
Multivariate analysis by Cox proportional hazards regression model for survival and total mortality in 2,864 patients with well-differentiated thyroid cancer.
| β coefficient | Hazard ratio | 95% confidence interval | p value | ||
|---|---|---|---|---|---|
| Lower bound | Upper bound | ||||
| Age (year) | 0.071 | 1.074 | 1.0598 | 1.0880 | 0.0000 |
| Gender (F/M) | 0.275 | 1.317 | 0.9743 | 1.7790 | 0.0733 |
| SPM∗ (without/with SPM) | 0.860 | 2.363 | 1.6987 | 3.2861 | 0.0000 |
| Postop 131I accumulative dose (mCi) | 0.000 | 0.999 | 0.9995 | 1.0004 | 0.7388 |
| Radio therapy (no/yes) | 1.289 | 3.628 | 2.5705 | 5.1209 | 0.0000 |
| TNM stage (SI/SII/SIII/SIV) | 0.260 | 1.305 | 1.1317 | 1.5056 | 0.0003 |
| Postop 1-month Tg (ng/mL) | 0.000 | 1.000 | 1.0000 | 1.0001 | 0.0000 |
| Tumor size (cm) | 0.0462 | 1.047 | 0.9896 | 1.1082 | 0.1099 |
| Thyroid operative method (less than total/total thyroidectomy) | −0.2960 | 0.744 | 0.5023 | 1.1014 | 0.1395 |
∗SPM: second primary malignancy.