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. 2016 Apr 12;7:507. doi: 10.3389/fmicb.2016.00507

Table 1.

Effect of probiotics (single or mixed culture) on treatment of Atopic Dermatitis (AD) in humans.

Reference Probiotics Outcome
Majamaa and Isolauri, 1997 Lactobacillus rhamnosus strain GG SCORAD score improvement (P = 0.008)
Rosenfeldt et al., 2003 L. rhamnosus + L. reuteri Positive effect of probiotics seen in allergic subjects (P = 0.04)
Kirjavainen et al., 2003 L. rhamnosus strain GG or L. GG SCORAD decrease (P = 0.02)
Viljanen et al., 2005 L. rhamnosus strain GG Positive effect seen only in IgE-sensitized infants (P = 0.036)
Weston et al., 2005 L. fermentum SCORAD decrease (P = 0.03)
Passeron et al., 2006 L. rhamnosus/synbiotics No significant difference between synbiotics and placebo
Sistek et al., 2006 L. rhamnosus + B. lactis Positive effect seen only in food-sensitized children (P = 0.047)
Brouwer et al., 2006 L. rhamnosus strain GG or L. rhamnosus No significant difference between probiotics and placebo
Fölster-Holst et al., 2006 L. rhamnosus strain GG No significant difference between probiotics and placebo
Grüber et al., 2007 L. rhamnosus strain GG No significant difference between probiotics and placebo
Roessler et al., 2008 L. paracasei + L. acidophilus + B. lactis No significant effects of probiotics
Chernyshov, 2009 L. rhamnosus 95%, L. helveticus 5% SCORAD decrease in subjects not used topical steroids was shown only in probiotic group (P < 0.01)
Gerasimov et al., 2010 L. acidophilus + B. lactis SCORAD decrease (P = 0.001)
Woo et al., 2010 L. sakei SCORAD decrease (P = 0.008)
Cukrowska et al., 2010 L. casei + L. paracasei Clinical improvement seen mostly in children with IgE-dependent atopic eczema
Gobel et al., 2010 L. acidophilus, or B. lactis/— No beneficial effects observed
van der Aa et al., 2010 B. breve/synbiotics Improvement in IgE-sensitized infants (P = 0.04)
Yoshida et al., 2010 B. breve SCORAD decrease (P = 0.034)
Wu et al., 2011 L. salivarius/ / synbiotics SCORAD decrease at 8 week (P = 0.022)
Farid et al., 2011 mixture/synbiotics SCORAD decrease (P = 0.001)
Gore et al., 2012 L. paracasei or Bifidobacterium No significant difference between probiotics and placebo
Yesilova et al., 2012 Bifidobacterium bifidum + L. acidophilus + L. casei + L. salivarius SCORAD decrease (P = 0.0015)
Han et al., 2012 L. plantarum SCORAD decrease (P = 0.0015)
Iemoli et al., 2012 L. salivarius; + B. breve SCORAD decrease (P < 0.001)
Drago et al., 2011 L. salivarius SCORAD decrease (P < 0.001)
Niccoli et al., 2014 L. salivarius LS01 SCORAD and itch improvement