Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Apr 11;213(1):109–125. doi: 10.1083/jcb.201510043

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016 El Azzouzi et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 4. — MT-MMP signals at podosomes persist longer than podosomal F-actin. (A and B) TIRF micrographs of macrophage expressing Lifeact-RFP to detect F-actin–rich podosome cores (A) and MT1-MMP-pHluorin (B). The center of mass of each podosome-associated signal was tracked, and tracks were colored according to their duration, as indicated. (C and D) Statistical analyses of track duration of podosomal F-actin and podosome-associated MT1-MMP. Each dot in C represents track duration of a single podosomal signal. Red bar indicates mean ± SEM. Note higher mean of MT1-MMP-pHluorin signals and also higher amounts of respective signals persisting for >50 min, which is plotted in D as the mean ± SEM percentage of total tracks. **, P < 0.01.