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. 2016 Apr 12;6:24182. doi: 10.1038/srep24182

Table 2. Fenestration pathway diameters and the residues contributing to the narrowest point of different hERG models.

Model Diameter of closest fenestration point Residues contributing to the narrowest point
hERG-KvAP-m6 1.98 Å 1st Subunit: F557, F619
2nd Subunit: L646
hERG-MthK–I 1.71 Å 1st Subunit: F619, M651, I655
2nd Subunit: L646, M645
hERG-KcsA–I 1.27 Å 1st Subunit: T623, Y652
2nd Subunit: M645, S649
hERG-Kv1.2 1.03 Å 1st Subunit: F557, F619
2nd Subunit: L646
hERG-MthK-O No path could be found at the discussed lateral fenestration site