Table 1. Comparison of brain region FA values between the DMD group and healthy controls (mean ± SD).
Location | DMD | Controls | t | P |
---|---|---|---|---|
Parietal lobe WM | ||||
Left | 0.482±0.063 | 0.458±0.051 | 1.081 | 0.291 |
Right | 0.463±0.063 | 0.430±0.046 | 1.523 | 0.141 |
Frontal lobe WM | ||||
Left | 0.407±0.093 | 0.380±0.079 | 0.803 | 0.430 |
Right | 0.417±0.087 | 0.378±0.070 | 1.259 | 0.220 |
Genu of corpus callosum | 0.775±0.066 | 0.801±0.093 | −0.805 | 0.429 |
Splenium of corpus callosum | 0.790±0.123 | 0.883±0.047 | −2.441 | 0.029* |
Caput nuclei caudati | ||||
Left | 0.132±0.030 | 0.154±0.050 | –1.279 | 0.213 |
Right | 0.138±0.031 | 0.148±0.053 | –0.572 | 0.573 |
Occipital lobe WM | ||||
Left | 0.653±0.074 | 0.636±0.074 | 0.576 | 0.570 |
Right | 0.657±0.068 | 0.675±0.101 | –0.523 | 0.606 |
Anterior cingulate | ||||
Left | 0.172±0.045 | 0.166±0.057 | 0.294 | 0.7711 |
Right | 0.180±0.052 | 0.179±0.069 | 0.053 | 0.958 |
Posterior cingulate | ||||
Left | 0.178±0.039 | 0.183±0.038 | –0.375 | 0.717 |
Right | 0.179±0.033 | 0.192±0.032 | –1.022 | 0.317 |
Lenticular nucleus | ||||
Left | 0.121±0.028 | 0.112±0.027 | –0.791 | 0.437 |
Right | 0.114±0.027 | 0.125±0.024 | –1.128 | 0.270 |
Posterior limb of internal capsule | ||||
Left | 0.761±0.033 | 0.742±0.072 | 0.891 | 0.384 |
Right | 0.787±0.023 | 0.752±0.079 | 1.592 | 0.132 |
Anterior limb of internal capsule | ||||
Left | 0.626±0.090 | 0.624±0.088 | 0.071 | 0.944 |
Right | 0.635±0.068 | 0.606±0.094 | 0.881 | 0.387 |
Thalamus | ||||
Left | 0.272±0.064 | 0.293±0.055 | –0.874 | 0.391 |
Right | 0.284±0.048 | 0.272±0.055 | 0.589 | 0.562 |
Temporal lobe WM | ||||
Left | 0.464±0.073 | 0.497±0.090 | –1.010 | 0.323 |
Right | 0.495±0.080 | 0.444±0.086 | 1.564 | 0.131 |
Hippocampus | ||||
Left | 0.163±0.042 | 0.155±0.037 | 0.516 | 0.611 |
Right | 0.148±0.044 | 0.154±0.036 | –0.413 | 0.683 |
Superior cerebellar peduncle | ||||
Left | 0.752±0.043 | 0.753±0.072 | –0.015 | 0.988 |
Right | 0.761±0.040 | 0.763±0.070 | –0.135 | 0.894 |
Middle cerebellar peduncle | ||||
Left | 0.738±0.059 | 0.760±0.088 | –0.923 | 0.365 |
Right | 0.774±0.075 | 0.797±0.060 | –0.874 | 0.391 |
*, P<0.05. FA, fractional anisotropy; DMD, Duchenne muscular dystrophy; WM, white matter.