Table 3.
Quantitative data from the live/dead viability assay
| Stimuli | Mean % ± SEM | P value |
|---|---|---|
| UPEC 2 control | 5 ± 2 | |
| UPEC 2 CORM-2 | 61 ± 18 | 0.0208* |
| UPEC 2 cefotaxime | 76 ± 8 | 0.0011** |
| ESBL 1 control | 6 ± 2 | |
| ESBL 1 CORM-2 | 60 ± 16 | 0.0135* |
| ESBL 1 cefotaxime | 5 ± 1 | |
| TG1 control | 13 ± 2 | |
| TG1 CORM-2 | 85 ± 9 | 0.0003*** |
| TG1 cefotaxime | 4 ± 1 |
Data show the ratio of dead bacteria (expressed as a percentage) after 24 h exposure to CORM-2 (500 μM), cefotaxime (0.512 μg/ml) or control (DMSO) evaluated by a live/dead viability assay. The ratio of dead bacteria was calculated by manual counting of four randomly selected quadrants (in total covering ¼ from each image) from a representative part of each well. The data are presented as mean ± SEM. (n = 3) *P < 0.05, **P < 0.01, ***P <0.001; CORM-2 or cefotaxime versus control