Table 1.
Body weight and fasting blood glucose in CON, CON +100 mg/kg/day berberine, diabetic, and diabetic +100 mg/kg/day berberine rats at 4 and 8 weeks after STZ-injection in Experiment I
Initial | 4 Week after STZ-injection | 8 Week after STZ-injection | ||||
---|---|---|---|---|---|---|
Body weight (g) | Blood glucose (mM) | Body weight (g) | Blood glucose (mM) | Body weight (g) | Blood glucose (mM) | |
CON (n = 20) | 195.0 ± 25.7 | 4.2 ± 1.2 | 423.5 ± 55.8 | 5.2 ± 0.9 | 501.0 ± 75.6 | 5.6 ± 1.5 |
CON + berberine (n = 20) | 186.5 ± 28.1 | 3.8 ± 2.2 | 417.9 ± 65.3 | 4.1 ± 1.2 | 483.5 ± 72.1 | 4.5 ± 1.7 |
Diabetic (n = 20) | 190.0 ± 23.4 | 3.6 ± 1.3 | 270.3 ± 46.3* | 21.9 ± 5.4* | 251.0 ± 52.7* | 25.91 ± 6.6* |
Diabetic + berberine (n = 20) | 187.0 ± 25.5 | 4.1 ± 1.6 | 327.0 ± 51.2#,* | 16.5 ± 4.5#,* | 353.0 ± 58.3#,* | 14.8 ± 4.3#,* |
CON control rats, CON + berberine control rats administrated with berberine (100 mg/kg/day), Diabetic diabetic rats, diabetic + berberine diabetic rats administrated with berberine (100 mg/kg/day). * P < 0.05 vs. CON and # P < 0.05 vs. diabetic rats