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. 2016 Apr 12;11:37. doi: 10.1186/s13000-016-0486-2

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© Sugita et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig 2 — Representative images of sarcomatoid carcinoma after synovial sarcoma was excluded. a: The tumor had a pseudoglandular structure and a sheet-like proliferation of cuboidal tumor cells. b: Tumor cells were positive for cytokeratin AE1/AE3 on IHC. c: Tumor cells were negative for bcl-2 on IHC. Infiltrating lymphocytes alone were bcl-2 positive. d: FISH analysis revealed no SS18 split signals. Nuclei showed more than two pairs of orange and green signals with a polyploidy pattern (arrows)