Table 2.
Comparison of the pathological diagnosis of the study sites and expert review by FISH analysis
| Histological type | Study site | Expert review | FISH | ||
|---|---|---|---|---|---|
| Positive | Negative | ND | |||
| Myxoid liposarcoma | 24 | 24 | 22 | 0 | 2 |
| Synovial sarcoma | 21 | 18 | 16 | 4a | 1b |
| Mesenchymal chondrosarcoma | 6 | 6 | 3 | 0 | 3 |
| Extraskeletal Ewing sarcoma | 5 | 5 | 4 | 0 | 1 |
| Alveolar soft part sarcoma | 5 | 5 | 5 | 0 | 0 |
| Alveolar rhabdomyosarcoma | 5 | 5 | 4 | 1 | 0 |
| Clear cell sarcoma | 5 | 5 | 5 | 0 | 0 |
| Extraskeletal myxoid chondrosarcoma | 2 | 2 | 1 | 1 | 0 |
| Dermatofibrosarcoma protuberans | 1 | 1 | 1 | 0 | 0 |
| Angiomatoid fibrous histiocytoma | 1 | 1 | 1 | 0 | 0 |
| Desmoplastic small round cell tumor | 1 | 1 | 1 | 0 | 0 |
| Total | 76 | 73 | 63 | 6 | 7 |
aFour FISH-negative cases of synovial sarcoma included 2 MPNSTs, 1 sarcomatoid carcinoma, and 1 synovial sarcoma with SS18-SSX fusion detected by RT-PCR
bOne FISH ND case with SS18-SSX fusion detected by RT-PCR
ND, not detected, MPNST malignant peripheral nerve sheath tumor