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. 2016 Apr 11;7:9. doi: 10.1186/s13227-016-0047-5

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© Langenbacher and De Tomaso. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Maximum likelihood phylogenetic analysis of Tgfβ-f and other TGF-β family members. Unrooted phylogenetic tree constructed by maximum likelihood analysis using RAxML with 504 replicates for bootstrap, the JTT substitution matrix, and empirical frequencies. Botryllus Tgfβ-f is marked by an arrow. Families of TGF-β proteins are labeled and indicated by vertical lines. Nodes are labeled with bootstrap values in units of percentage. The scale bar for branch lengths indicates the mean number of inferred substitutions per site