Table 4.
Lipid parameters, enzymatic antioxydant activity/polymorphism and CHD severity
| Parameters | 0-vessel (n = 13) | 1-vessel (n = 42) | 2-vessels (n = 35) | 3-vessels (n = 16) |
|---|---|---|---|---|
| Total cholesterol (mmol/L) | 4.11 ± 1.03 | 4.26 ± 1.07 | 4.59 ± 1.03 | 5.36 ± 1.41* |
| HDL-cholesterol (mmol/L) | 0.86 ± 0.28 | 0.84 ± 0.26 | 0.81 ± 0.29 | 0.79 ± 0.23 |
| LDL-cholesterol (mmol/L) | 3.02 ± 0.93 | 3.15 ± 1.01 | 3.49 ± 1.04 | 4.19 ± 1.39* |
| Triglycerides (mmol/L) | 1.14 ± 0.63 | 1.27 ± 0.65 | 1.34 ± 0.97 | 1.89 ± 1.00* |
| SOD activity, (U/gHb) | 1246.9 ± 242.15 | 1112.4 ± 141.37 | 1065.6 ± 194.28 | 864.3 ± 229.08**, ‡ |
| SOD genotypes, n (%), (CC/CT/TT) | 4/6/3 | 10/21/11 | 7/18/10 | 3/7/6 |
| (30.77/46.15/23.08) | (23.81/50.0/26.19) | (20.0/51.43/28.57) | (18.75/43.75/37.5) | |
| GPx activity, (U/gHb) | 38.90 ± 7.89 | 44.09 ± 11.32 | 42.94 ± 11.15 | 43.65 ± 12.64 |
| GPx genotypes, n (%), (CC/CT/TT) | 7/8/1 | 22/17/3 | 21/12/2 | 9/6/1 |
| (53.85/38.46/7.69) | (52.38/40.47/7.14) | (60.0/34.29/5.71) | (56.26/37.5/6.25) |
* P < 0.05 compared with 0-vessel disease and P = 0.001 with 1-vessel disease
** P < 0.001 compared with 0-vessel disease and with 1-vessel disease and P = 0.002 with 2-vessels disease
‡ P < 0.001 compared with 0-vessel disease, 1-vessel disease and 2-vessels disease