Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Apr 11;9:19. doi: 10.1186/s12920-016-0178-5

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Mucaki et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 5 — Predicted Alteration in UTR Structure Using mFOLD for Variants Flagged by SNPfold. Wild-type and variant structures are displayed, with the variant indicated by a red arrow. a Predicted wild-type structure of CDH1 5’UTR surrounding c.-71. b Predicted CDH1 5’UTR structure due to c.-71C > G variant. c Predicted wild-type TP53 3’UTR structure surrounding c.*485. d Predicted TP53 5’UTR structure due to c.*485G > A variant. e Predicted wild-type TP53 3’UTR structure surrounding c.*826. f Predicted TP53 5’UTR structure due to c.*826G > A variant. ^§SHAPE analysis revealed differences in reactivity between mutant and variant mRNAs, confirming alterations to 2° structure