Figure 2.

Pathological changes in the injured spinal cord of rats under a light microscope (hematoxylin-eosin staining, × 200).

(A) Sham group: distinct processes, darkly stained plump nuclei. (B) I90R0 group: slightly dense cytoplasm, lightly stained swollen nuclei. (C) I90R24 group: neurons were spindle-shaped; nuclei shifted, became small, and fragmented. (D) I90R48 group, neuronal cells became spin-dle-shaped; nuclei fragmented and disappeared. Sham, I90R0, I90R24 and I90R48: sham, 90-minute ischemia 0-hour, 24-hour and 48-hour reperfusion groups, respectively. Arrows point to neurons.