Table 1. Characteristics of SPS3 Participants by treatment group at baseline.
| Overall | Higher BP | Lower BP | ||
|---|---|---|---|---|
| “Usual” | “Intensive” | |||
|
| ||||
| n | 2610 | 1309 | 1301 | P-value |
| Age (years) | 63 (11) | 64 (11) | 63 (11) | 0.34 |
| Male | 1655 (63%) | 862 (66%) | 793 (61%) | 0.01 |
| Race | ||||
| Non-Hispanic White | 1300 (50%) | 641 (49%) | 659 (51%) | 0.75 |
| Black | 413 (16%) | 205 (16%) | 208 (16%) | |
| Hispanic | 834 (32%) | 430 (33%) | 404 (31%) | |
| Other/multiple | 63 (2%) | 33 (3%) | 30 (2%) | |
| Region | ||||
| North America | 1672 (64%) | 835 (64%) | 837 (64%) | 0.87 |
| Latin America | 647 (25%) | 330 (25%) | 317 (24%) | |
| Spain | 291 (11%) | 144 (11%) | 147 (11%) | |
| Smoking | ||||
| Current | 506 (19%) | 255 (19%) | 251 (19%) | |
| Past | 1069 (41%) | 525 (40%) | 544 (42%) | |
| Never | 1035 (40%) | 529 (40%) | 506 (39%) | 0.65 |
| BMI (kg/m2) | 29 (7) | 29 (8) | 29 (6) | 0.27 |
| Diabetes | 950 (36%) | 469 (36%) | 481 (37%) | 0.54 |
| Hypertension | 2337 (90%) | 1176 (90%) | 1161 (89%) | 0.62 |
| SBP (baseline) | 143 (19) | 144 (19) | 142 (18) | 0.10 |
| SBP (3 mo) | 133 (16) | 137 (15) | 130 (15) | <.0001 |
| SBP (9 mo) | 132 (15) | 137 (15) | 127 (14) | <.0001 |
| eGFR (ml/min/1.73m2) | 80 (19) | 80 (18) | 80 (19) | 0.59 |
| eGFR category at baseline: | ||||
| <60 | 410 (16%) | 195 (15%) | 215 (17%) | 0.25 |
| >60 | 2198 (84%) | 1113 (85%) | 1085 (83%) | |
Data are presented as Mean (SD) or numbers (percent).
SBP=systolic blood pressure in mmHg
eGFR= glomerular filtration rate estimated by CKD Epi equation in ml/min/1.73m2
2 persons are missing creatinine data at baseline, but have at least two values at follow-up.