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. Author manuscript; available in PMC: 2016 Apr 12.
Published in final edited form as: Diabetes Metab Res Rev. 2015 Jan;31(1):39–49. doi: 10.1002/dmrr.2542

Figure 4. Effect of the EGFRtk inhibitor and p-65NFκB shRNA lenti-viral particles (n=5) on.

Figure 4

-Endothelium-dependent relaxation in thoracic aorta in response to cumulative doses of ACh (10−8−3.10−5 M) in rings from aorta, pre-contracted with phenylephrine (PE, 10−5 M), from db−/db− incubated with either AG1478 (EGFRtk inhibitor) or p-65NFκB shRNA lenti-viral particles (A, C). #P < 0.05 for db−/db− vs. db−/db− + AG1478. @P < 0.05 for db−/db−, db−/db− + scrambled vs. db-/db− + P 65 shRNA

Western blot analysis and quantitative data (n=5) in homogenized thoracic aorta from db−/db− incubated with either AG1478 (EGFRtk inhibitor) or p-65NFκB shRNA lenti-viral particles, showing P-p-65, T-p-65 (B, D) and β-actin.