Table 1.
Body weight (g) | Blood Glucose (mg/dl) | |
---|---|---|
Control | 24.19 ± 0.48* | 132.3 ± 0.89* |
Control + DHMEQ | 25.88 ± 1.06* | 141.6 ± 3.28* |
Control + IKK-NBD peptide | 25.52 ± 0.81* | 140 ± 7.0* |
db−/db− | 42.29 ± 0.57 | 393.7 ± 20.17 |
db−/db− + DHMEQ | 41.33 ± 0.63 | 401.6 ± 20.12 |
db−/db− + IKK-NBD peptide | 38.16 ± 0.42 | 400 ± 14.8 |
db−/db-p-50NFkB-/- | 38.58 ± 1.90 | 340.03 ± 18.12 |
db−/db-PARP-1-/- | 38.81 ± 2.11 | 380.42±11.44 |
Data (means ± SE)
Blood glucose and body weight measurements from control, type 2 diabetic mice (db−/db−) treated with and without DHMEQ or IKK-NBD peptide, double knockout mice db−/db-p50NFκB and double knockout db−/db-PARP-1.
P < 0.05 for control, control treated with DHMEQ or IKK-NBD vs. db−/db−, db−/db− treated with DHMEQ or IKK-NBD, db−/db-p50NFκB and double knockout db−/db-PARP-1.