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. 2016 Apr 12;12(4):e1005570. doi: 10.1371/journal.ppat.1005570

Fig 2. ToxR binds to promoter regions on all four major Vibrio pathogenicity islands.

Fig 2

ToxR ChIP enrichment of the promoter regions of selected genes located on horizontally acquired islands (A) VPI-1, (B) VSP-1, (C) VSP-2, and (D) VPI-2. Enrichment of a non-ToxR-dependent promoter region of icd is shown as the negative control. ToxR enrichment of indicated promoter regions is statistically significant compared to the control. ****p < 0.0001; **p < 0.01; *p < 0.05, unpaired two-tailed Student’s t test. Mean with standard error of the mean (SEM) is shown.