Table 1.
Demographic characters | TN group (n = 20) | NR group (n = 20) | SVR group (n = 20) | Control group (n = 10) |
---|---|---|---|---|
Sex | ||||
Male : female | 19:1 | 17:3 | 17:3 | 4:6 |
Age | ||||
Range (mean ± SD) | 19–54 (42 ± 10.4) | 21–54 (43.5 ± 8.6) | 20–51 (40.3 ± 7.8) | 42–64 (56 ± 6.8) |
HCV viral load (106 IU/mL, [mean ± SD]) | 1.3 ± 1.2 | 0.9 ± 0.8 | NA | NA |
Distribution of liver inflammatory grade | ||||
Grade 1–2 | 12 | 11 | 14 | |
Grade 3–4 | 8 | 9 | 6 | NA |
Distribution of liver fibrosis stage | ||||
Stage 1–2 | 14 | 13 | 18 | |
Stage 3–4 | 6 | 7 | 2 | NA |
ALT (IU/mL [mean ± SD]) | 50.9 ± 25.8 | 37 ± 22.5 | 32.5 ± 26.7 | 21 ± 7.4 |
AST (IU/mL [mean ± SD]) | 36.5 ± 21.9 | 32.2 ± 23 | 25.9 ± 18.9 | 23 ± 11 |
ALT, alanine aminotransferase; AST, aspartate aminotransferase; NA, not applicable; NR, non-responders; SVR, sustained virologic response; TN, treatment naïve.