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. 2016 Apr 12;10(4):e0004617. doi: 10.1371/journal.pntd.0004617

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© 2016 Benítez et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 4 — The data are presented as mean TryS activity (%) ± 2 S.D. (n = 4) as function of Log₁₀ concentration (nM) of compound adjusted to a four-parameter Boltzmann sigmoidal equation. Representative dose-response plot obtained for MOL2008 (IC₅₀ = 0.14 ± 0.03 μM; slope plot 0.38 ± 0.03) and for FS-554 (IC₅₀ = 0.32 ± 0.73 μM; slope plot 0.37 ± 0.03).