Table 3. Features of LC and H_N upon acidification in the presence of membranes (LUV).

Features in presence of LUV	LC	HN
Trp1	Exposed from pH 5.9 to 4.2	Buried from pH 6.2 to 3.82
Membrane binding3	From pH 5.5 to 4.5	From pH 5.5 to 3.5
Membrane permeabilization4	From 5 to 3.5	From 4.5 to 3.5
Influence over the other domain	?	Moderates membrane interaction

¹Trp fluorescence

²Not shown

³FRET

⁴Fluorescent dye release from LUV