Fig 5. SOCS2 overexpression had no effect on newborn neuron survival after TBI.

The perilesional cortex of saline or Epo-treated SOCS2Tg and WT mice was analysed after moderately-severe TBI at 35d for EdU⁺NeuN⁺ newborn neurons. EdU⁺NeuN⁺ cells were present in both WT and SOCS2Tg perilesional cortex and a representative image of SOCS2Tg saline control cortex is shown (A-D). Panel D is the merged image of panels A-C. Scale bars = 100 μm. An example of a co-labelled cell is indicated by the arrow. No genotype differences in numbers of EdU⁺NeuN⁺ cells (E) were seen. Results show mean ± SEM; n = 7–8 mice/group (E).