Figure 3.

Global mRNA analysis of RRP40 depleted cells. RNASeq-based expression changes of RRP40 knockdown vs. EGFP control cells. Y-axes display log₂-fold changes of individual transcript levels while x-axes show the mean normalized expression (fragment counts normalized by size factors). Data were computed by the DESeq2 software.²⁹ Individual RefSeq protein coding genes are shown in black and significantly differentially expressed genes (p_adj = FDR < 0.1) are colored red. Dots corresponding to DAP and CTSZ mRNAs are highlighted.