Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Aug 14;12(10):1152–1158. doi: 10.1080/15476286.2015.1076612

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 The Author(s). Published with license by Taylor and Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

PMC Copyright notice

Figure 2. — Method development for the detection and quantification of dm⁵C and rm⁵C by LC-MS/MS. (A) Elution profiles of DNA oligonucleotide hydrolysate, spiked with S. cerevisiae RNA SIL-IS and [D₃]dm⁵C monitored by UV-absorption and mass chromatograms from LC- MS/MS. (B) Shows the elution profiles of a hydrolyzed RNA sample, spiked with both internal standards as well as the corresponding MS/MS data. (A and B) show distinct contamination of the samples with the matching m⁵C derivative.