Figure 6.
Role of linc-NeD125 in apoptosis. (A) Left panel: qRT-PCR analysis of Bcl-2 and Bax mRNA levels in linc-NeD125 and GFP overexpressing BE(2)-C cell lines upon 3 days of doxycycline-treatment. –Dox samples were set as 1. Gapdh mRNA was used as a loading control. Right panel: Bax/Bcl-2 mRNA ratio as evaluated from values reported in left panel. Histograms show mean values ± SEM from three independent experiments. *p < 0.05; **p < 0.01. (B) Bax/Bcl-2 ratio derived from qRT-PCR profiling of Bax and Bcl-2 mRNA (shown is Fig. S8) during in vitro BE(2)-C differentiation. Time points (days) of RA treatment are indicated below.