rsp5-1 |
degradation of 25S rRNA |
|
|
53 |
|
|
accumulation of poly(A)+ RNA in the nucleus |
|
71 |
rsp5-19 |
degradation of 18S and 25S rRNA (Northern and FISH analysis) |
|
|
53 |
|
decreased total rate of ribosomes |
|
|
53 |
|
reduced level of polysomes and 80S ribosomes |
|
|
53 |
|
|
accumulation of poly(A)+ RNA in the nucleus |
|
90 |
|
|
|
accumulation of tRNALeu precursors (Northern analysis) |
53 |
|
|
|
accumulation of tRNATyr and tRNAMet in the nucleus (FISH analysis) |
90 |
rsp5-3 |
inhibition of nuclear export of the pre-60S subunit |
|
|
52 |
|
accumulation of 35S pre-rRNA |
|
|
52 |
|
decreased level of 20S and 27S pre-rRNAs |
|
|
52 |
|
reduced level of mature 18S, 5.8S and 25S rRNAs |
|
|
52 |
|
degradation of 18S and 25S rRNA |
|
|
53 |
|
|
accumulation of poly(A)+ RNA in the nucleus |
|
52 |
|
|
|
accumulation of tRNALeu and tRNATyr in the nucleus (FISH analysis) |
52 |
|
|
|
accumulation of primary transcripts for tRNALeu and tRNAArg-Asp (Northern analysis) |
52 |
rsp5-ww2 |
|
accumulation of poly(A)+ RNA in the nucleus |
|
71 |
rsp5-ww3 |
|
accumulation of poly(A)+ RNA in the nucleus |
|
71 |
rsp5-A401E |
|
accumulation of HSF1 and MSN2/4 mRNAs in the nucleus |
|
72 |
rsp5Δ |
|
accumulation of poly(A)+ RNA in the nucleus |
|
71 |
|
|
accumulation of mRNAs encoding Pgk1, Ssa1, Ssa2 and Ssa3 in the nucleus |
|
71 |